This exhibit features a unique bioreactor designed to cultivate and mature bioartificial blood vessels under lifelike conditions. Inside, a pulsating flow of nutrients simulates the dynamics of the human bloodstream, supporting the natural maturation of the bioartificial blood vessels.
This exhibit features a unique bioreactor designed to cultivate and mature bioartificial blood vessels under lifelike conditions. Inside, a pulsating flow of nutrients simulates the dynamics of the human bloodstream, supporting the natural maturation of the bioartificial blood vessels.
The process begins with 4D bioprinting – an advanced technique that combines collagen, sugar molecules derived from brown algae, and human endothelial cells into a living structure. During the maturation phase, the printed bioartificial blood vessels are placed in the bioreactor, where carefully controlled pressure and biochemical signals guide their growth and development.
These engineered bioartificial blood vessels represent a promising step toward future applications in heart surgery, vascular transplants, and regenerative medicine.
Credits:
Tobias Torp, Jannek Grocholl, Julian Pfarr, Karina Zitta, Martin Albrecht, Micha Pfarr, Rouven Berndt
